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Genomic and cDNA libraries are essential tools in molecular biology, used to store large quantities of genetic material from an organism. The construction of these libraries involves different procedures based on the type of genetic material being analyzed—genomic DNA or complementary DNA (cDNA). To construct a genomic library, the first step is to extract high-quality genomic DNA from the organism of interest. This DNA is then fragmented into smaller pieces using physical (e.g., sonication) or enzymatic methods (e.g., restriction enzymes). These fragments are then ligated into vectors such as plasmids or bacteriophages, which are capable of replicating _______ __________ _______ _________ _____ ____ ______ _________ ___ _________ ________ _____.
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