Describe fluid mosaic model of biological membranes.
The fluid mosaic model, proposed by S.J. Singer and G.L. Nicolson in 1972, describes the structure of biological membranes as a dynamic and flexible arrangement of lipids and proteins. This model has become the cornerstone of our understanding of membrane architecture and its functional properties in living cells.
According to the fluid mosaic model, the membrane is primarily composed of a lipid bilayer, where the hydrophobic tails of phospholipids face inward, shielded from the aqueous environment, while the hydrophilic heads are oriented toward the water on both sides of the membrane. This lipid bilayer forms the basic structural framework of the membrane, providing both flexibility and selective permeability to the membrane.
The term "fluid" in the model emphasizes the lateral movement of lipids and proteins within the membrane. The lipid molecules are not fixed in place but can __________ ____ _______ ____ _________ ____ ___ __________ _________ ______.
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