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Thyroid hormones, primarily thyroxine (T4) and triiodothyronine (T3), are critical regulators of metabolism and growth. Biochemically, T4 is a prohormone that is converted to the more active T3 in target tissues by deiodinase enzymes. Both hormones are synthesized from tyrosine and iodine within the _____ ____ ____ __________ ____ _____ __________ _________.
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