Define enzyme and coenzyme. Explain models for mechanism of enzyme action in detail with diagram. 

Enzymes  are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. Almost all metabolic processes in the cell need enzyme catalysis in order to occur at rates fast enough to sustain life.: 8.1  Metabolic pathways depend upon enzymes to catalyze individual steps. The study of enzymes is called enzymology and the field of pseudoenzyme analysis recognizes that during evolution, some enzymes have lost the ability to carry out biological catalysis, which is often reflected in their amino acid sequences and unusual 'pseudocatalytic' properties.Enzymes are known to catalyze more than 5,000 biochemical reaction types.Other biocatalysts are catalytic RNA molecules, called ribozymes. Enzymes' specificity comes from their unique three-dimensional structures.

A coenzyme is defined as an organic molecule that binds to the active sites of certain enzymes to assist in the catalysis of a reaction. More specifically, coenzymes can function as intermediate carriers of electrons during these reactions or be transferred between enzymes as functional groups.For example, during the conversion of pyruvate to acetyl coenzyme A (CoA), several coenzymes including free CoA, thiamine pyrophosphate ____ _______ __________ ____ _____ ___ __________ __________ ______ _____.
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