Define and describe an O₂ dissociation curve. What are the effects of high temperature and carbon dioxide (CO₂) concentration on this curve?

The O₂ dissociation curve is a graphical representation of the relationship between the partial pressure of oxygen (PaO₂) and the percentage of hemoglobin (Hb) saturation with oxygen. It is typically sigmoidal (S-shaped) due to cooperative binding, where the binding of one O₂ molecule to hemoglobin increases the affinity for subsequent molecules. This curve is crucial for understanding oxygen transport and release in tissues. __________ _______ _________ _____ ___ _____ __________ __________.
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