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DNA replication in prokaryotes and eukaryotes shares many basic principles, such as the need for a template strand, complementary base pairing, and the involvement of DNA polymerases. However, there are several differences in the mechanisms and regulation of replication between these two groups of organisms. In prokaryotes, replication begins at a single origin of replication, typically located at the "oriC" site in _________ ________ ______ ______ ________ ___.
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