Briefly explain the preparative applications of size exclusion chromatography. 

Size Exclusion Chromatography (SEC), also known as Gel Filtration Chromatography, is a chromatographic technique used for separating and purifying molecules based on their size. It exploits the differences in molecular size and shape to separate molecules within a sample. SEC has several preparative applications in various fields, particularly in biochemistry, pharmaceuticals, and biotechnology. Here's a brief explanation of its preparative applications:

1. Protein Purification: SEC is commonly used in protein purification to separate proteins of different sizes within a complex mixture. By choosing _________ ___ _____ ______ _______ _________ __________ ________ ________ _________ _______ _______.
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