Briefly discuss the factors affecting drug metabolism.

Drug metabolism is a critical process that affects the efficacy and safety of pharmacological treatments. Several factors influence how drugs are metabolized in the body:

1. Genetic Factors: Individual genetic variations can significantly impact drug metabolism. Polymorphisms in genes encoding for metabolizing enzymes (such as cytochrome P450 enzymes) can alter enzyme activity, leading to variations in drug clearance and efficacy among individuals. ______ ___ ________ _____ __________ ____.
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