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People abuse drugs for a variety of complex and interrelated reasons, ranging from biological and psychological factors to social and environmental influences. One significant reason is the biological predisposition of individuals. Some people have genetic vulnerabilities that make them more susceptible to substance dependence. Research shows that genes can influence how the brain’s reward system responds to drugs, increasing the likelihood of repeated use and eventual addiction. Neurochemical imbalances, particularly involving dopamine pathways, can also make certain ________ ______ __________ __________ ________.
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