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Eicosanoids are biologically active lipid compounds derived from 20-carbon polyunsaturated fatty acids, primarily arachidonic acid. They are synthesized in almost all tissues and act as local signaling molecules. The major classes of eicosanoids include prostaglandins, thromboxanes, leukotrienes, and lipoxins. These molecules are not stored but are _____ ______ _________ ___ ______ ________ __________ _________ _______ ______.
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