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Substance abuse refers to the harmful or hazardous use of psychoactive substances such as alcohol, tobacco, and illicit drugs, leading to significant public health and hygiene concerns. From a public health perspective, substance abuse contributes substantially to the global burden of disease through increased morbidity, mortality, and disability. It is ______ __________ ____ _____ ______ ______ _____ ________ ____ _____.
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