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Regulated protein degradation is a fundamental mechanism that ensures precise control of cellular processes by selectively removing specific proteins at the appropriate time. In cell cycle control, this process is essential for maintaining the correct order and timing of events such as DNA replication, mitosis, and cytokinesis. The ubiquitin–proteasome system plays a central role by tagging target proteins with ubiquitin molecules, marking them for _________ _______ __________ _________ ____.
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