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Poor compliance to treatment in individuals with schizophrenia is a significant concern in mental health care. It not only leads to symptom relapse, increased hospitalization rates, and impaired functioning but also affects long-term prognosis and quality of life. Understanding the reasons behind non-compliance is essential for designing effective interventions. Compliance to treatment in schizophrenia involves regular intake of prescribed medication, engagement with psychosocial therapies, and adherence to follow-up appointments. Various biological, psychological, social, and systemic factors contribute to poor compliance in these individuals. One of the primary reasons for poor compliance is the lack of insight, also known as anosognosia, which is a common symptom of schizophrenia. Many individuals with schizophrenia do not recognize that they have a mental illness. This lack of insight is associated with damage or dysfunction in specific brain areas and is not merely a psychological denial. As a result, patients may not see the need for medication or treatment and may resist any form of intervention. Without insight, the motivation to adhere to a treatment plan is significantly reduced. Side effects of antipsychotic medication also play a major role in non-compliance. First-generation antipsychotics are often associated with extrapyramidal symptoms such as tremors, rigidity, and restlessness. Second-generation antipsychotics, though considered to have a better side effect profile, can still cause weight gain, sedation, sexual dysfunction, and metabolic changes. These side __________ ____ __________ _________ ___ ______ _____ _____ _____ ____ _____ _____.
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