Thexylborane

(i) Disimylborane

What is DIBAL? Give the method of its preparation. Which groups can be reduced using this reagent? Give any three examples of the compound which can be reduced using DIBAL.

 What is Lindlar's catalyst? Give the products of reaction of mandelic acid and naphthalene using hydrogenation.

Explain using suitable diagram the mechanism of catalytic hydrogenation of an alkene.

 Discuss the disconnections for the synthesis of paracetamol. Also write its scheme of synthesis. Draw the general scheme/mechanism of Stille coupling reaction. Give examples of some additives which are used to increase the rate of these reactions.

Give the product of reaction of oxepine with maleic anhydride.

 [2,2,0] hexa-2,5-diene

(ii) 1,4- cyclohexadiene

 Draw the products of the following:

(i) Reduction of quinoline with different reagents.

(ii) Oxidative cleavage of quinoline

(iii) Bromination of quinoline

 Give any two examples of synthetic antimalarial drugs with structure wherein a quinoline moiety is present.

How did Emil Fischer synthesise purine? Give the sequence of reactions.

 Describe the uses of benzotrioles.

Benzotriazole is nitrated

 Benzimidazole reacts with formaldehyde

 Benzimidazole reacts with acrylonitrile

) Give the products formed when
 

Chlorination of benzothiophene

Nitration of benzothiophene

) Vilsmeier-Haack reaction of benzofuran

Bredereck reaction